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Methyldopa reduces elevated blood pressure by relaxing and dilating (widening) blood vessels.

Methyldopa 250 mg
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60 pills
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90 pills
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Drug Uses

Methyldopa lowers blood pressure by decreasing the levels of certain chemicals in your blood. This allows your blood vessels (veins and arteries) to relax (widen) and your heart to beat more slowly and easily. Methyldopa is used to treat hypertension (high blood pressure).

How Taken

Use Methyldopa as directed by your doctor.
  • Take Methyldopa by mouth with or without food.
  • Do not take iron salts within 3 hours before or 2 hours after taking Methyldopa.
Ask your health care provider any questions you may have about how to use Methyldopa.

Drug Class and Mechanism

Methyldopa is an alpha-2 receptor agonist. It reduces elevated blood pressure by relaxing and dilating (widening) blood vessels. Blood flows more freely and at a lower pressure through dilated blood vessels.

Missed Dose

If you miss a dose of Methyldopa and are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.


Store Methyldopa at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep in a tight, light-resistant container. Keep Methyldopa out of the reach of children and away from pets.

Possible Side Effects

Check with your doctor if any of these most common side effects persist or become bothersome:
  • dizziness; drowsiness; dry mouth; headache; weakness.
Seek medical attention right away if any of these severe side effects occur:
  • severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; continuing fatigue; diarrhea; joint or muscle pain; swelling of the legs or feet; unexplained fever; vomiting; weight gain; yellowing of the skin or eyes.

More Information

Methyldopa is to be used only by the patient for whom it is prescribed. Do not share it with other people.

If your symptoms do not improve or if they become worse, check with your doctor.

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