Before you buy Insulin Glargine (Lantus) online
What is Insulin Glargine (Lantus)?
Lantus is a long-acting insulin analogue created to overcome disadvantages of traditional short-acting insulin-based drugs. The main active agent of the medicament is Insulin Glargine. It helps diabetic patients to manage glucose levels, which are associated with food consumption. The mechanism of Insulin Glargine’s action is similar to your body’s normal production of the hormone after the ingestion of food. The drug comes in convenient SoloSTAR pen supplied with a dose selector, which greatly simplifies the administration of insulin.
Is it For Me?
Insulin Glargine is intended for keeping levels of insulin steady in individuals suffering from diabetes that requires using analogs of insulin. Only your healthcare expert can decide whether the drug is right for you.
The medicament is counter indicated in the following cases:
age under 6 (the medicament hasn’t been tested in children of this age);
increased sensitivity (intolerance) to the active agent of the remedy or to its auxiliary component(s).
Pregnant females should use the medicament with caution.
How do I choose the right dosage?
The product comes in 100IU/ml (100 Units per milliliter) pens. Don’t choose the dosage on your own, this can be done only by your prescriber. When you know your dosage, you can adjust the amount of injected drug (in Units) by turning the dosage selector on the syringe.
Don’t force the selector to turn!
How do I take Insulin Glargine (Lantus)?
The medication is approved for once-a-day administration. It should be administered subcutaneously, at the same time of the day (this time, as well as the dosage, should be chosen by the doctor). Recommended places for injections include thighs, shoulders, and abdominal area. Sites for injections should be alternated with each new administration (within the abovementioned areas).
Don’t make intravenous injections with Lantus. It may lead to the severe hypoglycemia due to the sharp rise of insulin in your blood.
What are the mechanisms behind Insulin Glargine (Lantus)?
In terms of pharmacokinetics, the medicament resembles the activity of non-diabetic β cells in the pancreas organ. Insulin Glargine is an exact replica of human insulin that is poorly soluble in neutral environment. Lantus injections contain acidic environment, therefore insulin inside the syringe is dissolved in the liquid. After being injected under the skin, the drug enters into chemical reactions resulting in the formation of micro-precipitates, from which small quantities of the active agent are continuously released over a long period of time.
The most significant effect of the medicament is the regulation of metabolic processes related to the use of sugar. It reduces glucose content in the blood by stimulating its consumption by tissues, in particular muscle tissue, & fat deposits. In addition, Lantus suppresses the formation of glucose inside the liver. Other effects of insulin are inhibition of fat breakdown processes and enhancing protein synthesis.
What is Insulin Glargine (Lantus) uptake time?
The medicament begins to act in several hours after injection. It isn’t a drug with instant action. Lantus consists of small crystals that slowly release the main agent, providing long-term effect (18-26 hours) without a sharp increase in insulin levels in the blood (the so-called “peakless” profile).
How efficient is Insulin Glargine (Lantus)?
The effectiveness of the medication is confirmed by patients’ experience and multiple scientific studies.
For example, according to the research by Owens D. & Griffiths S. (2002), the drug showed great results in treating type 1 & type 2 diabetes.
Does Insulin Glargine (Lantus) have any side effects?
The medicament is well tolerated but it can cause some adverse effects.
Among them are:
Hypoglycemia. This is the most frequent adverse event that can occur if the applied dosage is higher than the body's need for insulin.
Lipodystrophy. This is a condition under which the body cannot synthesize fat. The risk of developing lipodystrophy is significantly reduced if the patient constantly changes the injection points.
Allergic reactions on the skin. The drug can cause redness, painful sensations, itching, and hives.
Visual impairment and other rare side effects, such as the formation of antibodies to insulin.
To make sure that the medication is safe for your health, inform your prescriber about having the following conditions:
kidney or liver ailments;
hypokalemia (lowered potassium rates in the blood flow);
ketoacidosis caused by diabetes.
If you take Actos or Avandia, you must tell the healthcare professional about it. Some oral antidiabetic meds may increase the risk of heart ailments occurrence if they are used in combination with insulin-based drugs.
Any essential tips on Insulin Glargine (Lantus) use?
The drug shouldn’t be used for ketoacidosis treatment. In such cases, short-term insulins are injected intravenously.
Don’t mix Lantus with other drugs. Don’t use insulin syringe for making other meds injections. Don’t reuse needles.
Concomitant ailments require closer monitoring of the level of sugar. In some cases, the body's need for insulin increases.
Always tell your prescriber about any meds you take. Some of them may enhance hypoglycemic action of Lantus, while others may decrease this action.