Erythromycin

Before you buy Erythromycin online

Erythromycin is used in patients with the following conditions: pneumonia caused by Mycoplasma pneumoniae, Chlamydia psittaci (Ornithosis), or Chlamydia pneumoniae (TWAR), whooping cough, diphtheria, urogenital infections caused by chlamydia trachomatis. In the following conditions Erythromycin should be reserved for patients with penicillin hypersensitivity or where penicillin is inappropriate for other reasons: pharyngotonsillitis, acute otitis media, community-acquired pneumonia, skin and soft tissue infections.

The ester of Erythromycin is hydrolysed after absorption, to free active erythromycin. The effect is primarily bacteriostatic and is exerted by binding to the bacterial ribosome, the protein synthesis, thus inhibited.

Erythromycin influences bacterial metabolism so that they cannot reproduce. Since the bacteria are short-lived, this means that they are rapidly declining in number. Usually you will feel better within three days. If you don't, you should contact the doctor again.

Swallow the tablets with water. The tablets should be taken immediately before a meal for the active substance to get absorbed by the body as well as possible. It also reduces the risk of upset stomach. Alcohol does not affect the efficacy of the medication.

The drug should be received in the prescription dose which is tailored to the person using the medication. Therefore, it is important to follow the dosing instructions printed on the label on the medicine package. Then you get the best possible results of the treatment and reduce the risk of side effects. Dose and duration of treatment depends on the infection being treated for. Uusually Erythromycin Novum is prescribed to be taken twice a day. If you experience stomach discomfort, the dose may instead be divided and taken four times daily.

If you forget to take a dose, take it as soon as you remember. But if it is less than half the time left until the next dose is better to skip the missed dose and continue as usual.

Hypersensitivity to the active substance, other macrolides or to any of the excipients. Concomitant use with astemizole, cisapride, disopyramide, ergot alkaloids (such as ergotamine and dihydroergotamine), pimozide, or terfenadine.

Erythromycin should not be used concomitantly with simvastatin, atorvastatin and lovastatin. Treatment with these drugs should be discontinued during treatment with Erythromycin online.

Erythromycin is contraindicated in patients with congenital long QT syndrome or as long QT syndrome, family history (if not excluded by ECG) and in patients with known acquired QT prolongation.

Erythromycin Novum can interact with many other drugs. It is therefore very important to tell the doctor what other medications they are taking before taking Erythromycin Novum. Some examples are:

Erythromycin - contraindications, warnings and precautions

Since erythromycin is mainly excreted via the liver, caution should be exercised when administering to patients with hepatic impairment.

There are reports that erythromycin may aggravate the symptoms of myasthenia gravis patients.

Diarrhea / pseudomembranous colitis caused by Clostridium difficile (CDAD) may occur with use of nearly all antibacterial agents including erythromycin and can vary in severity from mild diarrhea to fatal colitis. Patients with diarrhea should be monitored closely for CDAD. Careful medical history is necessary since CDAD has been reported to occur several weeks after the administration of antibacterial agents. If CDAD is suspected or confirmed, if possible ongoing erythromycin therapy be discontinued.

Erythromycin has been associated with prolongation of the QT interval and infrequent cases of arrhythmia. Post-marketing cases of torsades de pointes spontaneously reported in patients receiving erythromycin. Deaths have been reported. Erythromycin should be avoided in patients with known prolongation of the QT interval, patients with ongoing pro-arrhythmic conditions such as untreated hypokalemia or hypomagnesemia, clinically significant bradycardia, and in patients receiving class IA antiarrhythmics (quinidine, procainamide), or class III (dofetilide, amiodarone, sotalol). Elderly patients may be more susceptible to drug-associated effects on the QT interval.

Erythromycin should not be used during and two weeks after treatment with CYP3A4 inducers (such as rifampicin, phenytoin, carbamazepine, phenobarbital, St. John's wort). Concomitant treatment with these medicinal products is likely to result in subtherapeutic levels of erythromycin and therefore encompass a risk of treatment failure.

Erythromycin is an inhibitor of CYP3A4 and should only be used under specific circumstances during treatment with other drugs metabolized by CYP3A4. Cases of infantile hypertrophic pyloric stenosis (IHPS) in infants after erytromycinbehandling have been reported. Usefulness of Erythromycin therapy can be weighed against the potential risk of developing IHPS. Parents should be advised to contact their physician if vomiting or irritation when feeding occurs.

Prolonged or repeated use of erythromycin may result in overgrowth of non-susceptible bacteria or fungi. If super-infection occurs, erythromycin therapy discontinued and appropriate therapy instituted.

There is a risk of developing vision impairment after exposure to erythromycin. An existing genetic metabolic mitochondrial dysfunction, such as Leber hereditary optic neuropathy (LHON) and autosomal dominant optic atrophy (ADOA), play a contributing role in the development of vision loss in some patients.

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